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Monday, July 27, 2020 | History

3 edition of The epithelial dynamics in the mouse tongue following irradiation injury found in the catalog.

The epithelial dynamics in the mouse tongue following irradiation injury

Richard Thomas Glass

The epithelial dynamics in the mouse tongue following irradiation injury

by Richard Thomas Glass

  • 18 Want to read
  • 37 Currently reading

Published .
Written in English


Edition Notes

Statementby Richard Thomas Glass.
Classifications
LC ClassificationsMicrofilm 40133 (Q)
The Physical Object
FormatMicroform
Paginationvii, 92 leaves
Number of Pages92
ID Numbers
Open LibraryOL2162226M
LC Control Number88893479

Recommend this book. Email your librarian or administrator to recommend adding this book to your organisation's collection. Disorders of Voluntary Muscle. 8th edition George Karpati; Edited by David Hilton-Jones, Kate Bushby, Robert C. Griggs; Online ISBN: Author: George Karpati. THERAPY OF LETHAL RADIATION INJURY WITH NICOTINIC ACID DERIVATIVES. I. EXPERIMENTAL INVESTIGATION OF THE ACTION OF 7- 2-HYDROXY(NHYDROXYETHYL-N-METHYLAMINO)PROPYL -1,3-DIMETHYLXANTHINE-PYRIDINECARBOXYLATE BEFORE AND AFTER LETHAL WHOLEBODY IRRADIATION OF THE SHITE MOUSE .

We evaluated the mitigating effects of fibroblast growth factor 4 and 7 (FGF4 and FGF7, respectively) in comparison with long acting protected graft copolymer (PGC)-formulated FGF4 and 7 (PF4 and PF7, respectively) administered to C57BL/6J mice a day after exposure to LD50/30 ( Gy) partial body irradiation (PBI) which targeted the gastrointestinal (GI) by: 1. Tubular damage following ischemic renal injury is often reversible, and tubular epithelial cell (TEC) prolif-eration is a hallmark of tubular repair. Macrophages have been implicated in tissue repair, and CSF-1, the principal macrophage growth factor, is expressed by TECs. We therefore tested the hypothesis that CSF

Culture of Epithelial Cells () Paperback – January 1, by Unknown (Author) See all 3 formats and editions Hide other formats and editions. Price New from Used from Paperback "Please retry" $ $ $ Paperback $ Author: Unknown.   Generally, squamous cell carcinomas of skin are slow-growing tumors; though SCC of Lip is an aggressive form of cancer. These lesions are observed on the lower lip in a majority of the cases. The oral cavity may also be affected. The tumor may be single; though, it is not uncommon to find multiple tumors in an individual.


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The epithelial dynamics in the mouse tongue following irradiation injury by Richard Thomas Glass Download PDF EPUB FB2

Parkins CS, Fowler JF, Yu S. A murine model of lip epidermal/mucosal reactions to X-irradiation. Radiother Oncol. Nov; 1 (2)– Xu FX, van der Schueren E, Ang KK.

Acute reactions of the lip mucosa of mice to fractionated irradiations. Radiother Oncol. Mar; 1 (4)–Cited by:   Summary. Epithelial proliferation in the ventral surface of mouse tongue follows a pronounced circadian rhythm with a peak in mitotic activity at a.m., preceded by a wave of DNA synthesis 8 h earlier.

Nearly all cells (85%) pass through G2 and mitosis immediately after the S-phase; they subsequently divide again, usually after 2 or 3 days, Cited by: Both bleomycin (BLM) and local X-irradiation (25 kV) induce denudation in the tongue epithelium of the C3H-Neuherberg mouse in a dose-dependent manner.

In the present study the effect of BLM alone and of combined single doses of drug and radiation were studied using the incidence of epithelial denudation as the by: 3. Briefly, the events in the lower ileum of the mouse following whole body irradiation with a large dose (3 rad) are as follows: mitosis and DNA synthesis disappear rapidly.

During the following 3 / 4 days, 1 / 2 to 2 / 3 of the crypt cells disappear through cell death or through emigration onto the villi following precocious maturation [normally, cells mature only at a certain stage following mitosis Cited by: The present study hence focuses on the manifestation of early inflammatory changes in mouse tongue during daily fractionated irradiation and their potential modulation by pentoxifylline.

In the first two papers of this series (Potten et al. a, b) we presented an extensive cell kinetic description of our murine oral mucositis model (Wardley et al.

) and we present data in the following paper (Potten et al. c) showing how pretreatment with KGF reduces the severity of the oral mucositis induced by irradiation. In Cited by: Results On post-irradiation days 4 and 7, the epithelial layer on oral mucosa showed pronounced injury (shortening of the layer) and it is diminished by ALA pretreatment.

Author summary Ionizing Radiation (IR), alone or in combination with other therapies, is used to treat an estimated half of all cancer patients. Yet, we understand little about why some tumors cells respond to treatment while others grow back (regenerate).

We identified specific pools of cells within a Drosophila organ that are capable of regeneration after damage by by: 6. Start studying a and p lab quiz 2.

Learn vocabulary, terms, and more with flashcards, games, and other study tools. 36 Abstract-This report provides a review of early and late effects of radiation in 37 normal tissues and organs with respect to radiation prot. It was instigated ection 38 following a recommendation of ICRP (), and it provides updated estimates 39 of threshold doses for tissue injury defined at the level of 1% incidence.

Estimates 40 are given for morbidity and mortality File Size: 2MB. Clonal analysis of the origin of tongue cancer. To determine if the origin of 4-NQO-induced tongue tumors is monoclonal, we labeled all epithelial cells with random colors and followed their fates Cited by:   Notably, X-ray irradiation enhanced cell proliferation more in 5T4-knockout mice than in wild-type mice.

CONCLUSIONS: Our results suggest that 5T4, expressed in epithelial progenitors (taste stem/progenitor cells) and taste precursor cells, may influence the maintenance of taste papillae under both normal and injury : Yuka Takahashi, Hiroo Takahashi, Hiroo Takahashi, Peter L. Stern, Tadaaki Kirita, Akio Tsuboi, Akio.

Dose-Dependent Radiation-Induced Epithelial Injury in a Mouse Model of Head and Neck Fractionated Irradiation. It has been previously reported that severe damage in oral epithelial tissues develops by day 7–10 after high-dose local irradiation (up to 40 Gy given as a single dose or multiple fractions) (20).Cited by: It is detectable in the CNCC-derived mesenchyme adjacent to the tongue epithelium (Hosokawa et al., ) and in the tendons of the extrinsic muscles, which connect the tongue to the mandible, where Scx is also expressed.

TGFβ family members expressed in the CNCC regulate skeletal muscle development via tissue–tissue interactions (Figure ). Suppression of injury-induced epithelial-mesenchymal transition in a mouse lens epithelium lacking tenascin-C Sai-ichi Tanaka, 1 Takayoshi Sumioka, Norihito Fujita, Ai Kitano, Yuka Okada, 1 Osamu Yamanaka, Kathleen C.

Flanders,2 Masayasu Miyajima,3 Shizuya Saika 1 1Department of Ophthalmology, Wakayama Medical University, Wakayama, Japan; 2Laboratory of Cancer. the part of the skeletal system formed by the extremities, shoulder girdle, and pelvic girdle. a joint; the point at which two or more bones meet. wasting away; a decrease in size usually due to lack of use.

a painful soft tissue injury in which a flap of. Many powerful new techniques for the isolation and culture of epithelial cells have been developed in the past decade.

In Epithelial Cell Culture Protocols, a team of well-versed experimenters and clinical researchers share their best methods for establishing and maintaining epithelial cell cultures, for analyzing and studying their characteristics, and for using them to.

Up-Regulation of Autophagy Defense Mechanisms in Mouse Mesenchymal Stromal Cells in Response to Ionizing Irradiation Followed by Bacterial Challenge.

By Nikolai V. Gorbunov, Thomas B. Elliott, Dennis P. McDaniel, K. Lund, Pei-Jyun Liao, Min Zhai and Juliann G. Kiang. Submitted: July 9th Reviewed: December 4th Published: April 17th Cited by: 2.

As tongue cancer is one of the major malignant cancers in the world, understanding the mechanism of maintenance of lingual epithelial tissue, which is known to be the origin of tongue cancer, is unquestionably important. However, the actual stem cells that are responsible for the long-term maintenance of the lingual epithelium have not been identified.

Moreover, a simple Cited by: 1. However, after irradiation-induced injury, the cells rapidly entered the cell cycle and regenerated tongue epithelium.

These results suggest that Bmi1-positive LESCs are important for the tissue maintenance of lingual epithelium in the physiological state as well as for rapid regeneration after by: 1.

Additionally, in a host of tissues, Wnt/β-catenin signaling functions in regeneration following injury, including IR dam27,28,29,30,31,32,33,34; thus here we investigated if Author: Dany Gaillard, Lauren A. Shechtman, Sarah E.

Millar, Linda A. Barlow.Second, galectin-7 has been described as a proapoptotic factor involved in the epidermal response after UVB injury.

Hence, following an early report in which galectin-7 was identified as one of the first genes responding to overexpression of the p53 tumor suppressor gene in DLD-1 human colon cancer cells (Polyak et al., ), Bernerd et al.Gamma radiation decreased mouse survival and body weight.

Irradiated mice first demonstrated mortality 9 d after irradiation and showed no survival 23 d after irradiation. The mean survival time (ST 50) was 12 d.

All non-irradiated mice survived (Fig. 4A). Irradiated mice demonstrated significant body weight loss 10 d after irradiation and Cited by: